Angiopoietin inhibitors functions to inhibit the vascular growth factor angiopoietin to curb several associated health complications. Angiopoietin regulates blood vessels angiogenesis, smooth muscle cells vasoconstriction, vasodilation and microvascular permeability.
Angiopoietin is of 4 types angiopoietin-1, 2, 3 and 4. The angiopoietin inhibitors therapeutics have diverse therapeutic role in solid tumours, cancers, vascular disease and asthma.
According to American Institute of Cancer Research Fund, there are over 18 million cancer cases worldwide, 9.5 million in men and 8.5 million in women, with lung and breast cancer are the most prevalent. Over 17.9 million die every year due to cardiovascular diseases, stated by the World Health Organization (WHO).
Angiopoietin with tyrosine kinase pathway are associated with diabetes, sepsis, malaria and hypertension, therefore understanding the mechanism of angiopoietin inhibition and developing angiopoietin inhibitors therapeutics would be beneficial for disease’ treatments.
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Recent clinical developments and research of angiopoietin inhibitors therapeutics or anti-angiopoietin antibodies have given positive outcomes for cancer. The global angiopoietin inhibitors therapeutics market is expected to elevate lucratively with the rising patient population, advancing research and healthcare.
Coronavirus has impacted the global angiopoietin inhibitors therapeutics market, especially in coronavirus prognosis wherein, Angiopoietin-2 acts as endothelial activation marker and mortality in critical coronavirus patients.
Angiopoietin Inhibitors Therapeutic Market: Drivers and Restraints
The global angiopoietin inhibitors therapeutics market drivers include the escalating research improving global health infrastructure successful clinical trials and pipeline drugs. The angiopoietin inhibitors therapeutics are used for cancer diabetic retinopathy diabetic nephropathy and asthma treatment.
Numerous research institutions pharmaceutical companies R&D along with governments’ funds and reimbursement are fuelling angiopoietin inhibitors therapeutics market growth.
However the restraining factors of global angiopoietin inhibitors therapeutics decelerate the market including angiopoietin-2 adverse reactions which is suspected to be associated with tyrosine-protein kinase receptor Tie-2 and VEGF.
Further research and rigorous clinical studies are required for efficacy and safety assurance.Although the overall global angiopoietin inhibitors therapeutics market is expected to grow further with progressing research and successful clinical trials of angiopoietin inhibitors therapeutics.
Angiopoietin Inhibitors Therapeutic Market: Overview
The global angiopoietin inhibitors therapeutics market is expected to grow lucratively with the increasing patients of cancer vascular diseases escalating research and healthcare.
By types of angiopoietin inhibitors Angiopoietin -2 inhibitors lead the segment with the massive research and clinical developments of angiopoietin -2 inhibitors such as trebananib MEDI3617 REGN910 CVX-060 for renal cell carcinoma solid tumours and breast cancers.
By application type solid tumours and cancers dominates the segment of angiopoietin inhibitors therapeutics market due to its vast applications into solid tumours and cancers. By distribution channels hospitals rule the segment with their advanced diagnostics medical facilities and high expenditures for angiopoietin inhibitors therapeutics.
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Angiopoietin Inhibitors Therapeutic Market: Regional Outlook
North America dominates the global angiopoietin inhibitors therapeutics market with its advancing research and technology well-developed medical infrastructures ongoing clinical trials key players rising cancer and vascular disease patients.
Europe angiopoietin inhibitors therapeutics market holds the second largest market driven by active research the rising burden of diseases and therapeutic demand. Asia-pacific angiopoietin inhibitors therapeutics market is growing at fastest pace due to the progressing research government’s favorable policies elevated drug developments and increasing cancer and diabetes patients.
Latin angiopoietin inhibitors therapeutics market is growing gradually with their progressing research. MEA and Africa angiopoietin inhibitors therapeutics market is also expanding future growth is expected with the advancing research and healthcare.
Angiopoietin Inhibitors Therapeutic Market: Key Players
The key players of angiopoietin inhibitors therapeutics market include
- Pfizer and Regeneron Pharmaceuticals.
The research report presents a comprehensive assessment of the market and contains thoughtful insights facts historical data and statistically supported and industry-validated market data. It also contains projections using a suitable set of assumptions and methodologies.
The research report provides analysis and information according to market segments such as geographies application and industry.
The report covers exhaust analysis on:
- Market Segments
- Market Dynamics
- Market Size
- Supply & Demand
- Current Trends/Issues/Challenges
- Competition & Companies involved
- Value Chain
Regional analysis includes:
- North America (U.S. Canada)
- Latin America (Mexico. Brazil)
- Western Europe (Germany Italy France U.K Spain)
- Eastern Europe (Poland Russia)
- Asia-Pacific excluding Japan (China India ASEAN Australia & New Zealand)
- Middle East and Africa (GCC Countries South Africa Northern Africa)
The report is a compilation of first-hand information qualitative and quantitative assessment by industry analysts inputs from industry experts and industry participants across the value chain.
Angiopoietin Inhibitors Therapeutic Market: Segmentation
The global angiopoietin inhibitors therapeutics market is segmented into types of angiopoietin inhibitors, applications, distribution channels and regions.
- Angiopoietin-1 inhibitors (AMG780, AB3120)
- Angiopoietin-2 inhibitors (Trebananib, MEDI3617, REGN910 CVX-060)
- Solid tumours and Cancers
- Vascular diseases (Diabetic Retinopathy, Diabetic Nephropathy)
- Detailed overview of parent market
- Changing market dynamics in the industry
- In-depth market segmentation
- Historical current and projected market size in terms of volume and value
- Recent industry trends and developments
- Competitive landscape
- Strategies of key players and products offered
- Potential and niche segments geographical regions exhibiting promising growth
- A neutral perspective on market performance
- Must-have information for market players to sustain and enhance their market footprint
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