An assay which simultaneously measures multiple analytes in a single cycle of the assay is known as a multiplex assay. Within a given application area of technology, multiplex assays can further stratify the analytes which are measured per assay. The term multiplex refers to the highest number of analyte measurement per assay. Detection of the state of all biomolecules of a given class (i.e. proteins and mRNAs) within a biological sample is the function of multiples assays in functional genomics where they are widely used to determine the effect of an experimental treatment. Multiplex assays are of two types namely, planar assay and bead-based assay. Planar microarrays, such as protein microarrays are characterised by ligands immobilised onto the plane surface in microspots onto a two-dimensional grid. Some of the commercially available planar microarrays are ImmunoCAPR ISAC. Bead-based assays also called as suspension or liquid array ligands are immobilised onto a microsphere called bead and captured analytes are detected using flow cytometric methods. Some of the examples of bead-based assay products are QUANTA Plex. Some of the multiplex techniques are DNA microarray, SAGE, multiplex PCR, and DNA sequencing by ligation.
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Global Multiplex Assay Market: Restraints
Multiplex assays cannot be used off-the-shelf for any new application and must be optimised to demonstrate safety and performance before being applied to any clinical sample. This requires considerable time and initial investment. Thus the development of the multiplex assay for clinical use is a cumbersome process that involves feasibility study to produce an assay with optimised parameters for every component analyte on the panel and evaluation of test system suitability. This factor is hampering the development of the global multiplex assay market. Apart from this, reproducibility crisis and complex clinical trial procedures for multiplex assay products are limiting the growth of the global market. The non-magnetic multiplex assay is more laborious to run which hindrances the growth of the global multiplex assay market.
Global Multiplex Assay Market: Key Regions
North America will continue to dominate the global market partly due to high research and development capability. While life science research and development activities in several ASEAN countries such as Malaysia would drive the growth of APAC multiplex assay market. Latin America multiplex assay market is expected to expand at below average CAGR owing to low penetration of multiplexing technology in the region.
Global Multiplex Assay Market: Key Market Players
QIAGEN N.V, Thermo Fisher Scientific, Inc., Luminex Corporation, Bio-Rad Laboratories, Inc and Illumina, Inc. are some of the key market players globally.
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