Global Insight Services have recently published a report on Lassa Fever – Drug Pipeline Landscape, 2022. The pipeline landscape report provides analysis of pipeline products based on several stages of development ranging from Discovery to Pre-Registration.
Lassa fever is an acute viral hemorrhagic illness caused by Lassa virus, a member of the arenavirus family of viruses. It is a hemorrhagic virus that can cause bleeding without any symptoms.
Lassa fever virus is a disease that is animal-borne or spread to humans from animals. It is spread to people through contact with household items, food, water, or air contaminated with the droppings or urine of infected multimammate rats (Mastomyces natalensis). The most common method of transmission is by consuming or inhaling rat urine or feces. It can also be spread through cuts and open sores. Person-to-person contact is possible via blood, tissue, secretions.
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Symptoms of Lassa fever include bleeding in the gums, nose, difficulty in breathing, cough, vomiting and diarrhea, hepatitis, swollen face, hearing loss, high or low blood pressure, tremors and other CNS conditions.
Diagnostic tests for Lassa fever are laboratory-based. Lassa fever is diagnosed by using enzyme-linked immunosorbent serologic assays (ELISA). These detect IgM and IgG antibodies and Lassa antigens. Reverse transcription-polymerase chain reaction (RT-PCR) can also be used in the early stages of the disease. Immunohistochemistry stains performed on tissue specimens can be used to make a post-mortem diagnosis.
Rehydration and treatment of symptoms can improve the of survival if there is an early diagnosis. Intravenous ribavirin given early in the course of illness is an effective treatment, in addition to support of fluid and electrolytes, oxygenation, and blood pressure.
Report Highlights
Global Insight Service’s, Lassa Fever – Drug Pipeline Landscape, 2022 report provides an overview of the Lassa Fever pipeline drugs. This report covers detailed insights on Lassa Fever drugs under development, assessment by target, mechanism of action, route of administration and molecule type. Product pipeline by companies, stage of development and key regulatory designations, deals and milestones have been presented to provide insights and thus help industry participants in their decision making. Lassa Fever pipeline report helps gain insights on drugs which are under development stage of drug development process across globally.
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Methodology
The research process includes extensive secondary research on public domain and other authentic sources to add or update the pipeline products information. The secondary research sources include, but are not limited to company websites, annual reports, financial reports, company pipeline chart, investor presentations and SEC filings, journals and conferences, and clinical trials registries.
Scope
The pipeline landscape report provides analysis of pipeline products based on several stages of development ranging from Discovery to Pre-Registration. The report provides a review of pipeline therapeutics by companies based on information derived from company and industry-specific sources. The pipeline report covers assessment of therapeutics by mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. Comprehensive profiles of the pipeline products with details such as company overview, development stage; molecule type, target, mechanism of action, route of administration, dosage form, regulatory designations, key deals, clinical trials, and key upcoming milestones are included.
Report Segmentation
- Assessment by Stage of Development
- Assessment by Companies
- Assessment by Target
- Assessment by Mechanism of Action
- Assessment by Molecule Type
- Assessment by Route of Administration
Key Players
- Inovio Pharmaceuticals
- Emergent BioSolutions Inc
- GeoVax Labs Inc
- Globavir Biosciences
- Kineta Inc.
- Medigen Inc
- Zalgen Labs LLC
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