According to a recent study by PMR, the market for Humanized Liver Mice Models is expected to reach over US$ 22.8 million in value by 2026’s end. High development potential is also predicted for the humanized liver mouse model market, with an average 4.6% annual growth rate through 2026.
Humanized Liver Mice Market Overview-
There are numerous humanized liver mouse models, such as TK-NOG mice, FRG KO mice, and uPA-SCID mice, among others. There are more research and development activities that need these models as a result of factors like rising liver cirrhosis rates, technological development of novel humanized liver mouse models, and rising FDA approvals for liver-based illness treatments. But throughout the anticipated time, it is anticipated that issues such as high shipping costs, the availability of substitutes, and the high cost of mice models will restrain the market’s expansion for humanized liver mice models.
The uPA-SCID mice are albumin enhancer/promoter-driven urokinase-type plasminogen and activator/severe combined immune-deficient animals. These transgene-induced liver diseases are treated in these animals by rapid postnatal transplantation of primary human hepatocytes. These mice are the most prevalent variety of humanized liver mouse models available and were among the first to be created with substantial chimerism. The Herpes Simplex Virus-1 Thymidine Kinase (HSVtk) transgene, which is largely driven by the albumin enhancer/promoter in the mice’s liver, is intended to be expressed in the TK-NOG mice. When treated with gancyclovir, this causes harm that is particular to the liver.
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Market Segmentation-
- The market for humanized liver mice has been divided into segments by model, application, end-user, and geography by PMR.
- The humanized liver mice models are further divided into the TK-NOG mice, FRG KO mice, and uPA-SCID mice.
- The humanized liver mice model market is divided into pharmaceutical companies, biotechnology firms, contract research organizations (CRO), and academic & research institutes based on end users.
- The CROs category is anticipated to have the largest market share in the market for humanized liver mice, followed by the academic & research institutes segment.
- The humanized liver mice model market is divided into pharmacokinetic studies, in-vivo liver toxicity tests, drug metabolism research, and other applications on the basis of application.
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Regional Segementation
The humanized liver mouse model’s primary regional market is anticipated to be North America. This is because both the public and private sectors support research efforts. Other elements that assist the expansion of the humanized liver mice model business in North America include government financing and support for patenting genetically modified mice. Due to the government’s shifting policies to promote the pharmaceutical and biopharmaceutical sectors in the area, China is likewise anticipated to be a lucrative regional market for humanized liver mice models.
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