Protein collagen is used in several fields, including food, biomedicine, and skincare. Various beneficial properties of collagen support its usage as a potential biomaterial as compared to other natural polymers and their synthetic equivalents. Collagen is a highly preferred biomaterial due to its biological properties such as high biocompatibility, biodegradability, and low antigenicity. Approximately 30% of all proteins in the body are made of this protein, which is primarily found in bones, ligaments, and tendons. These collagen peptides are also known as hydrolysed collagen. Primary sources of collagen are cattle, pigs, and fish, while minor sources include chicken, equines, rat tails, silkworms, and sheep. Gelatin is also known as a multifunctional ingredient due to its properties, such as gelation, water binding, foaming, elasticity, binding, emulsifying, film forming, and viscosity, which provide texture and stability to products. Several companies are focusing on these products, as the demand is increasing. This, in turn, is fueling the gelatin market and collagen peptide market.
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Rise in Social Awareness about Personal Well-being Increasing Demand for Nutraceuticals
Demand for nutritional supplements, such as collagen peptide and hydrolyzed gelatin, has increased due to rise in focus on health and lifestyle. People are choosing functional foods and nutraceuticals to ward off age-related illnesses and enhance quality of life. Applications of nutraceuticals are increasing due to factors such as easy accessibility, affordability, and awareness. The geriatric population and athletes use nutraceuticals, as these are rich sources of proteins and other essential supplements. The European Nutraceutical Association (ENA) estimates that malnutrition was responsible for 38.6% of deaths in developing countries such as China, India, and Brazil. Therefore, nutritional deficiencies are caused by the types of food that people eat, not by their socioeconomic class. Increase in age-related health concerns, economic growth, rise in health awareness, surge in geriatric population, and changing lifestyles are increasing the demand for nutraceuticals.
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Surge in Commercialization of Novel Collagen-based Drug Delivery Systems
Collagen-based drug delivery products used in various disease areas include collagen sponges, shields, liposomes, microspheres, and nanoparticles. Liposomes and nanoparticles are novel types of collagen-based drug delivery system for sustained release. Collagen is also widely used in the encapsulation of active pharmaceutical ingredients (API) to protect them from disintegration in acidic gastric juices.
Liposomes are superior carriers because these can encapsulate both hydrophilic and lipophilic drugs and protect them from degradation. Furthermore, they improve absorption rates and can function as an efficient solubilizing matrix. Liposome gel formulations outperform conventional formulations, resulting in higher patient compliance and efficacy. These advantages lead to increased acceptance of collagen-based liposome drug delivery systems, which in turn drives the collagen market. In comparison to other synthetic polymers, protein-based nano carriers (such as collagen, elastin, and fibronectin) have shown to be advantageous due to their low toxicity, lack of immunogenicity, high stability, and high nutritional value. Collagen nanoparticles possess high capacity for adsorption and high dispersion ability in water, which enables high sustained release of different drugs.
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High Number of Beneficial Properties Fueling Gelatin Segment
In terms of product type, the global collagen peptide and gelatin market has been bifurcated into collagen peptide and gelatin. Gelatin is known as a multifunctional ingredient because of its properties such as gelation, water binding, foaming, elasticity, binding, emulsifying, film forming, and viscosity, which drives its usage in various products. Utilization of gelatin to treat health-related issues, such as arthritis and joint pain, is increasing significantly, as it also aids in the treatment of skin and hair issues. Moreover, it is widely used in the manufacturing process of products that cater to wound healing market and empty capsule market.
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