The global cell culture media market size is expected to reach USD 10.2 billion by 2030, according to a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 12.1% from 2022 to 2030. Expansion of biosimilars and biologics, growth in stem cell research, and emerging bio-manufacturing technologies for cell-based vaccines are the major factors that are likely to drive the market. For instance, in October 2021, the Australian Government funded Australian-led stem cell research through USD 25 million in grants.
Cell Culture Media Market Report Highlights
- By product, the serum-free media segment held the largest revenue share of the market. This is attributed to the increasing gene and cell therapy research along with advantages offered by SFM, which in turn is likely to increase the adoption and anticipate market growth
- The biopharmaceutical production segment is expected to grow lucratively over the forecast period. Strategic activities by key biopharmaceutical companies, increasing R&D, demand for more reproducible and better-defined media and growing biosimilars market drives the segment growth
- By type, the liquid media segment held the largest revenue share of the market in 2021. This is attributed to increasing number of biopharmaceutical manufacturers, both downstream and upstream, are switching from premixed powders to liquid media and hence, propelling market growth
- By end-user, the pharma and biopharma companies segment held a larger share in 2021, owing to the expansion of the current manufacturing capacities coupled with increasing prevalence of chronic disease which in turn demands for novel therapeutic drugs
- North America dominated the market in 2021 due to the growth in the pharmaceutical and biotechnology industry, presence of high R&D investment, and the development of novel culture media products in the region
- In Asia Pacific, the market is expected to grow considerably in the future owing to the flourishing biosimilar medicine industry along with increasing investments by major market players to increase their presence in the region
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Cell culture media is a general word that refers to any gel or liquid created to support the health & growth of microorganisms and mammalian cells in an artificial environment. They are prepared by dissolving in distilled water & adjusting the final pH leve
l prior to sterilization. They provide a source of energy for cell growth and compounds that regulate cellular processes. It contains nutrients (both organic and inorganic), vitamins, salts, O2 and CO2 gas phases, proteins (from defined or undefined sources), carbohydrates, cytokines, growth factors, and cofactors. Some of the types of media include Serum-containing media, animal component-containing media, xeno-free medium, and chemically defined medium. Apart from assessing the complete nutritional composition, stable pH becomes vital for optimum microbial growth.
The expansion of clear, regulatory approval paths for biosimilars in emerging markets is generating great opportunities for biosimilar monoclonal antibodies. The availability of an approval pathway in the U.S., has led to new opportunities for bio manufacturers to enter major markets around the globe. Biosimilar versions of monoclonal antibodies have the probability to offer cost reductions of 25-30%, and many emerging market countries are vigorously developing pathways for approvals and are swiftly catching up. As this industry is expanding the key biopharmaceutical players are adopting robust culturing technologies to meet the increasing demand; thereby driving the growth of the market.
Moreover, there is growing interest in improving the stem cell culture, because this technology is being used extensively in research for studying the stem cell biology, as well as for therapeutic applications. Furthermore, funding related to this research field has augmented in recent years which has accelerated the growth of the market. In addition to this, key media manufacturers launched new products for stem cell research. For instance, in September 2021, Bio-Techne Corporation launched a novel medium for the maintenance and expansion of induced pluripotent stem cells having applications in both translational and research workflows.
The outbreak of COVID-19 pandemic has improved the demand for well-established cell-based vaccine production technologies. Moreover, it has given rise to a few scientific innovations, particularly in the production and testing of vaccine technology. For instance, the Vero line originated from the African green monkey kidney and has been extensively used for viral vaccine manufacturing. It has also been used for the development of various SARS-CoV variants. ProVeroTM1 Serum-free Medium is one such medium manufactured by Lonza Bioscience which is protein-free, and of non-animal origin designed to support the growth of Vero cells and MDCK.
Moreover, in many European countries, cell-based flu vaccines have been approved. A probable advantage of cell culture technology is that it authorizes faster start-up of the manufacturing of vaccines during the pandemic. Today, the development of superior biological models, the optimization of culture growth medium, and the reduced dependence on animal-derived components endure to drive the rapidly developing vaccine development.
On the other hand, ethical issues concerning the use of animal-derived products hinders the industry growth. For instance, FBS is collected from the blood of fetal calves is one of the major ethical issues of serum containing media. It is projected that 600,000 liters of FBS is achieved from up to 1.8 million bovine fetuses are produced globally every year, presenting momentous scientific and ethical challenges. To overcome this issue, numerous workshops were held in the past on the replacement of fetal bovine serum and possible ways to reduce the use of FBS in media.
Cell Culture Media Market Insights By Demographics
North America dominated the market and accounted for the largest revenue share. This major share can be attributed to the growth in the pharmaceutical and biotechnology industries, mounting approvals for cell culture-based vaccines, and rising incidence of diseases such as cancer coupled with investments and funding in cell-based research. In Asia Pacific, the market is estimated to grow fast owing to the increase in awareness associated with the use of the cell culture technique. Strategic activities by key players to expand their presence in the Asia Pacific countries to capture high market share is expected to offer lucrative opportunities.
Competitive Analysis By Major Companies
Key players in this industry are implementing various strategies including partnerships through mergers and acquisitions, geographical expansion, and strategic collaborations to expand their market presence. The company develops, produces, and markets feed supplements and media for cell cultures, particularly for the manufacturing of viral vectors that are used in vaccines and gene therapeutics. Some of the prominent players in the global cell culture media market include:
- Thermo Fisher Scientific Inc.
- Merck KGaA
- CYTIVA
- Sartorius AG
- FUJIFILM Irvine Scientific, Inc.
- Lonza Group AG
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Cell Culture Media Market Segmentation
Grand View Research has segmented the global cell culture media market based on product, application, type, end-user, and region:
- Cell Culture Media Product Outlook (Revenue, USD Million, 2018 – 2030)
- Cell Culture Media Application Outlook (Revenue, USD Million, 2018 – 2030)
- Cell Culture Media Type Outlook (Revenue, USD Million, 2018 – 2030)
- Cell Culture Media End-user Outlook (Revenue, USD Million, 2018 – 2030)
- Cell Culture Media Regional Scope Outlook (Revenue, USD Million, 2018 – 2030)
- List of Key Players of Cell Culture Media Market
Research Methodology
We employ a comprehensive and iterative research methodology focused on minimizing deviance in order to provide the most accurate estimates and forecasts possible. We utilize a combination of bottom-up and top-down approaches for segmenting and estimating quantitative aspects of the market. Data is continuously filtered to ensure that only validated and authenticated sources are considered. In addition, data is also mined from a host of reports in our repository, as well as a number of reputed paid databases. Our market estimates and forecasts are derived through simulation models. A unique model is created and customized for each study. Gathered information for market dynamics, technology landscape, application development, and pricing trends are fed into the model and analyzed simultaneously.
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About Grand View Research
Grand View Research provides syndicated as well as customized research reports and consulting services on 46 industries across 25 major countries worldwide. This U.S. based market research and consulting company is registered in California and headquartered in San Francisco. Comprising over 425 analysts and consultants, the company adds 1200+ market research reports to its extensive database each year. Supported by an interactive market intelligence platform, the team at Grand View Research guides Fortune 500 companies and prominent academic institutes in comprehending the global and regional business environment and carefully identifying future opportunities.
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