Human microbiomes refers to the aggregation of microorganisms that are present on and within the human body. Human microbiome is a full array of microorganisms such as bacteria, bacteriophage, fungi, protozoa and viruses. Factually humans have 10 times more of the microbial cells than human cells.
Path to genome sequencing has changed human microbiome research from focusing on identity characterizations to metagenomics strategies that reveal not only microbial species but also how microbial metabolic activities correlate with human health and disease. The interaction between the human microbiome and the immune system has an effect on several human metabolic activity. Research studies are going on to identify the relation between composition between the microbiome and infectious disease.
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Next-generation sequencing (NGS) has fueled studies capable of surveying the genomes of entire microbial communities, including those of unculturable organisms.Microbial transcriptomics, or metatranscriptomics, provides key insights into the expressed RNAs encoded by a group of organisms in a complex sample. High-quality metatranscriptomics data enables researchers to quantify gene expression changes, predict resistance or susceptibility to specific treatments, understand host-pathogen immune interactions, and track disease progression.
By Disease Type
· Obesity
· Diabetes
· Autoimmune Disorder
· Metabolic and Gastrointestinal Disorders
· Cancer
· Other Diseases
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