DNA probes are stretches of single-stranded DNA, utilized to identify the presence of complementary nucleic acid sequences (target sequences) by hybridization. Marked with a label like color or fluorescence, they allow researchers to detect a distinct sequence of DNA in a mixture. Firstly, the DNA sample is heated to separate the DNA strands after which the probe is applied.
The growing adoption of DNA probes in new disease identification has led to investments and foray of new players. Fact.MR, a global research and consulting firm, in its new report analyzes the DNA probes based diagnostics market in detail, offering comprehensive coverage on the key success factors.
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Key Challenges for the Market:
While DNA probes have been a welcome development in the global healthcare industry, there are potential associated demerits which are likely to hamper future expansion of the market. In numerous instances, differentiation between species is problematic while using 16S rRNA sequences due to similarity.
The global standard library of rRNA sequences is constantly expanding and continuously being updated, making it difficult to dismiss possibilities of a random hybridization event between a specifically designed probe and an undesired target organism.
Apart from this, recombination between the marker and disease alleles, and incorrect pedigree data or non-paternity leads to erroneous diagnosis. These factors are hampering the growth of the market.
Competitive Landscape:
With a rising elderly population and growing cases of infectious diseases and cancer, the DNA probes based diagnostics market is getting more competitive. The market is witnessing the entry of several newcomers. Consequently, established players are trying to hold their position by launching innovative products after comprehensive R&D.
For instance, BioMerieux conducted thorough research and developed ARGENE® Solution, which is a comprehensive automated solution devoted to centralized laboratories for the management of molecular biology tests to monitor viral infections in immune-compromised patients. It incorporatespolymerase chain reaction (PCR) technology with real-time NASBA® (Nucleic Acid Sequence-Based Amplification) technology.
Competitors identified in this market include, among others,
- Abbott Molecular
- Beckman Coulter Inc.
- Becton, Dickinson and Company
- bioMérieux
- Hoffmann-La Roche Ltd.
- GE Healthcare Life Sciences
- Luminex Corporation
- QIAGEN N.V.
- Siemens Healthineers
- Thermo Fischer Scientific Inc.
DNA Probes based Diagnostics Market Segmentation by Category:
· By Application :
- Infectious Diseases
- Cancer
- Genetic Predisposition
- Identity/forensics
- Others
· By Region :
- North America
- Latin America
- Europe
- East Asia
- South Asia
- Oceania
- Middle East & Africa (MEA)
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