A traditional Japanese food “Natto” is a food made from soybeans fermented by Bacillus natto, and has been eaten since about 1,200 years ago. Enzymes that Bacillus natto produce by fermentation include protease and Dr. Oshima at Hokkaido Imperial University reported its purification and characteristics. Since then, it was investigated as a serine protease, and, in 1980s, the enzyme that degrades fibrin proteins (a cause of thrombi) was named as “Nattokinase”. Nattokinase is found in the sticky part of Natto.
Functions of Nattokinase include directly degrading a fibrin (the main component of thrombi), activating pro-urokinase (precursor for urokinase that is an thrombolytic enzyme in the body) and increasing the amount of tissue plasminogen activator (t-PA) that produces a thrombolytic enzyme, plasmin. In addition, recent research has revealed that Nattokinase has a function of degrading plasminogen activator inhibitor, PAI-1 and reducing the euglobulin lysis time, and therefore, it has a function of improving the thrombolytic activity. Furthermore, the reduction of blood pressure has also been confirmed.
Global Nattokinase market is projected to reach US$ 52 million in 2029, increasing from US$ 33 million in 2022, with the CAGR of 8.0% during the period of 2023 to 2029. Influencing issues, such as economy environments, COVID-19 and Russia-Ukraine War, have led to great market fluctuations in the past few years and are considered comprehensively in the whole Nattokinase market research.
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Global key players of Nattokinase include Japan Bio Science Laboratory, Daiwa Pharmaceutical, Contek Life Science, etc. The top three players hold a share over 62%.
Asia-Pacific is the largest market, has a share about 61%, followed by North America, and Europe, with share 19% and 11%, separately.
In terms of product type, 10001-20000 Fu/g is the largest segment, occupied for a share of 57%.
Nattokinase can be mainly used in Dietary Supplement， Dietary Supplement has a share about 88%.
Scope of Nattokinase Market Report:
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Segment by Type:
- 0-10000 Fu/g
- 10001-20000 Fu/g
- Above 20001 Fu/g
Segment by Application:
- Dietary Supplement
- Others
Production by Region:
- China
- China Taiwan
- Japan
Leading Key Players of Nattokinase Market:
- Japan Bio Science Laboratory
- Daiwa Pharmaceutical
- Contek Life Science
- Sungen Bioscience
- Eiffel Biotech
- Vedan Biotechnology
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The Nattokinase report covers below items:
Chapter 1: Product Basic Information (Definition, type and application)
Chapter 2: Manufacturers’ Competition Patterns
Chapter 3: Production Region Distribution and Analysis
Chapter 4: Country Level Sales Analysis
Chapter 5: Product Type Analysis
Chapter 6: Product Application Analysis
Chapter 7: Manufacturers’ Outline
Chapter 8: Industry Chain, Market Channel and Customer Analysis
Chapter 9: Market Opportunities and Challenges
Chapter 10: Market Conclusions
Chapter 11: Research Methodology and Data Source
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