Breast tissue markers play a crucial role in mammography diagnostics, often implanted post-percutaneous biopsy following ultrasonic or stereotactic guidance. These markers aid in identifying harmless regions or tracking changes in treated malignant lesions during follow-up imaging. They come in various shapes, compositions, and some have bio-absorbable components, offering versatility in clinical use. Presently, ribbon, coil, and wing markers are commonly utilized due to their distinguishable appearances on mammograms, with newer ultrasound-detectable markers also emerging in the market. They are instrumental in guiding subsequent radiotherapy treatments, aiding in localization wire targets inserted before surgery.
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The global market for breast tissue markers is experiencing a surge in demand for biodegradable options. Traditional metal clips, often used as radio markers during biopsy procedures with a 3 mm diameter, pose drawbacks as they remain indefinitely in the breast tissue. This discourages some women from undergoing biopsies, especially if multiple markers are required for differentiating abnormal lesions in mammograms. Moreover, metal clips can migrate away from the biopsy site post-deployment, and their ferromagnetic properties cause complications during MRI scans, affecting the local magnetic field.
These limitations underscore the need for biodegradable markers, prompting increased interest and demand in the market. Biodegradable markers offer the advantage of naturally degrading over time, eliminating the need for their indefinite presence and mitigating migration issues, thus addressing concerns associated with traditional metal markers in breast tissue imaging procedures.