Market Definition
Peptides are a unique class of highly active and specific pharmaceutical compounds, molecularly poised between small molecules and proteins, yet biochemically and therapeutically diverse from both. The advantages of peptides, such as relative ease of synthesis, ready availability, and low toxicity, increased their applications in the pharmaceutical, nutritional, and cosmetic industries, resulting in high demand for rapid advancements in the technologies to enhance their synthesis.
Market Outlook
The global Peptide Synthesis Market was valued at 1.4 billion in 2022 and it is anticipated to grow up to USD 4.2 billion by 2032, at a CAGR of 11.6% during the forecast period.
The market for peptides has experienced significant growth due to their widespread adoption in the pharmaceutical and consumer healthcare industries. Peptides are being increasingly utilized in the treatment of various lifestyle disorders, including cancers, diabetes, and obesity. The rising prevalence of these metabolic and lifestyle disorders has created a favorable environment for the application of peptide therapeutics in the fields of oncology and metabolic disorders. According to data published by the International Diabetes Federation in 2021, there were 537 million adults (20-79 years) globally living with diabetes, which accounted for approximately 1 in 10 individuals. Additionally, 541 million adults were identified as having Impaired Glucose Tolerance (IGT), putting them at a high risk of developing type 2 diabetes. Peptide therapies like Glucagon-like peptide-1amide have gained popularity in pancreatic therapy as they stimulate insulin secretion postprandially. Consequently, the increasing number of diabetic patients is expected to drive the demand for peptide drugs and contribute to market growth in the foreseeable future.
The peptide synthesis market has also witnessed significant expansion due to increased research activities, novel product approvals, and enhanced funding for research and development. Furthermore, advancements in peptide synthesizers have provided additional advantages, further fueling market growth. An example of recent progress in this field is ISSAR Pharma’s announcement in April 2021 regarding the licensing of their peptide-based New Chemical Entities (NCEs), which have reached the pre-investigational new drug (IND) filing stage and obtained a United States patent. These notable developments in peptide drugs are expected to create a surge in market demand and drive the overall growth of the industry.
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Research Objectives
- Estimates and forecast the overall market size for the total market, across product, service type, type, end-user, and region
- Detailed information and key takeaways on qualitative and quantitative trends, dynamics, business framework, competitive landscape, and company profiling
- Identify factors influencing market growth and challenges, opportunities, drivers and restraints
- Identify factors that could limit company participation in identified international markets to help properly calibrate market share expectations and growth rates
- Trace and evaluate key development strategies like acquisitions, product launches, mergers, collaborations, business expansions, agreements, partnerships, and R&D activities
- Thoroughly analyze smaller market segments strategically, focusing on their potential, individual patterns of growth, and impact on the overall market
- To thoroughly outline the competitive landscape within the market, including an assessment of business and corporate strategies, aimed at monitoring and dissecting competitive advancements.
- Identify the primary market participants, based on their business objectives, regional footprint, product offerings, and strategic initiatives
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Global Peptide Synthesis Market Segmental Overview
The report analyses the global Peptide Synthesis Market based on Product, Technology, Application End-user, and Region.
Global Peptide Synthesis Market by Product
Based on the product, the global market for peptide synthesis is divided into equipment, reagents & consumables, and others. Out of these equipment segment accounted for substantial market share in the year 2022.. The development of innovative peptide synthesis equipment has greatly contributed to the rapid growth of this segment in the global market. For instance, in February 2017, researchers at MIT introduced a new piece of equipment that enables faster peptide synthesis compared to existing options. This automated machine can create links between amino acids in just approximately 37 seconds, allowing for the production of large quantities of customized peptides in a shorter timeframe. On the other hand, reagents and consumables have generated the highest revenue among other peptide synthesis products. This is mainly due to their regular use in peptide synthesis protocols. Furthermore, recent advancements in peptide coupling reagents are expected to further drive market growth in the upcoming years.
Global Peptide Synthesis Market by Technology
By technology, the industry is bifurcated into Solid Phase Peptide Synthesis (SPPS), Liquid Phase Peptide Synthesis (LPPS), and Hybrid & Recombinant Technology. Liquid-phase peptide synthesis has dominated the global market throughout the projected period, while solid-phase peptide synthesis has exhibited the fastest growth from 2022 to 2032. The integration of automation and advancements in both liquid and solid-phase peptide synthesis has significantly contributed to cost reduction in peptide synthesis, driving its adoption worldwide and leading to increased global revenue. Traditional studies suggest that solid-phase peptide synthesis is a suitable approach for GMP manufacturing and API process development, particularly for cost-effective synthesis of long peptide sequences (more than 10 amino acids) in smaller volumes. However, purification costs during solid-phase peptide synthesis can increase manufacturing costs at any production scale. On the other hand, liquid-phase peptide synthesis is commonly used for developing shorter peptide sequences and larger volumes. Hybrid approaches are employed for synthesizing long sequences in large volumes..
Global Peptide Synthesis Market by Application
Based on application, the industry is categorized into therapeutics, diagnosis, and research. The therapeutics segment, which includes various medical areas such as cancer, metabolic disorders, cardiovascular disorders, respiratory conditions, gastrointestinal disorders, infectious diseases, pain management, dermatology, central nervous system disorders, renal conditions, and others, was the leading revenue generator in the year 2022. This segment is anticipated to maintain its dominance throughout the forecast period.
On the other hand, the diagnosis segment is projected to experience the fastest growth from 2019 to 2026. The use of synthesized peptides in cancer treatment has significantly contributed to the revenue generated by the therapeutics segment, making it a major contributor in this market. Furthermore, within the therapeutics segment, the metabolic disorders segment is expected to exhibit the highest growth rate over the forecast period. This growth can be attributed to the presence of a robust pipeline and a substantial number of peptide candidates for treating type II diabetes. The discovery of novel peptides that play a crucial role in metabolic regulation is anticipated to provide valuable insights for the development of effective therapeutic approaches.
Global Peptide Synthesis Market by End-user
Based on end-user, the Peptide Synthesis market is divided into Pharmaceutical & Biotechnology Companies, Contract Development and Manufacturing Organization (CDMO), and Academic and Research Institutes. Among these, pharmaceutical and biotechnology companies are accounted for significant market share in 2022. This is owing to peptide therapies are gaining popularity in the pharmaceutical and biotechnology industries due to their cost-effectiveness, efficiency, and lower toxicity. The market for peptide synthesis is being driven by rapid advancements in peptide synthesizers and a robust pipeline of peptide therapeutics. In a 2022 article titled “Advances in oral peptide drug nanoparticles for diabetes mellitus treatment” published in Science Direct, it was highlighted that oral administration of peptide medications holds promise for treating diabetes mellitus. This approach is considered advantageous over traditional parenteral administration methods due to its simplicity and high patient compliance.
The growth of the market is further fueled by product launches, mergers, acquisitions, and the presence of competitors. An example of this is the world’s first “Peptide In A Pill” launched by Novo Nordisk India in January 2022. The peptide, Semaglutide, belongs to the GLP-1 receptor analog (GLP-1 RA) drug class and is used for managing type 2 diabetes. These developments are anticipated to drive the expansion of the pharmaceutical and biotechnology end-user segment in the peptide synthesis market.
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Major Players in the Global Peptide Synthesis Market
Market players are focusing on strategic collaborations to enhance their product offerings. Some prominent participants in the global Peptide Synthesis market include Bachem Holding AG, Thermo Fisher Scientific, Merck KGaA, GenScript Biotech Corporation, Kaneka Corporation, Biotage AB, Syngene International Ltd. , Mesa Laboratories inc. , CEM Corporation and ProteoGenix among others.
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Research Scope
- Scope – Highlights, Trends, Insights. Attractiveness, Forecast
- Market Sizing – Product Type, End User, Offering Type, Technology, Region, Country, Others
- Market Dynamics – Market Segmentation, Demand and Supply, Bargaining Power of Buyers and Sellers, Drivers, Restraints, Opportunities, Threat Analysis, Impact Analysis, Porters 5 Forces, Ansoff Analysis, Supply Chain
- Business Framework – Case Studies, Regulatory Landscape, Pricing, Policies and Regulations, New Product Launches. M&As, Recent Developments
- Competitive Landscape – Market Share Analysis, Market Leaders, Emerging Players, Vendor Benchmarking, Developmental Strategy Benchmarking, PESTLE Analysis, Value Chain Analysis
- Company Profiles – Overview, Business Segments, Business Performance, Product Offering, Key Developmental Strategies, SWOT Analysis.
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