The global Peptide Synthesis Market was valued at 1.4 billion in 2022 and it is anticipated to grow up to USD 4.2 billion by 2032, at a CAGR of 11.6% during the forecast period.
Peptides are a unique class of highly active and specific pharmaceutical compounds, molecularly poised between small molecules and proteins, yet biochemically and therapeutically diverse from both. The advantages of peptides, such as relative ease of synthesis, ready availability, and low toxicity, increased their applications in the pharmaceutical, nutritional, and cosmetic industries, resulting in high demand for rapid advancements in the technologies to enhance their synthesis.
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Market Trends and Drivers
The market for peptides has experienced significant growth due to their widespread adoption in the pharmaceutical and consumer healthcare industries. Peptides are being increasingly utilized in the treatment of various lifestyle disorders, including cancers, diabetes, and obesity. The rising prevalence of these metabolic and lifestyle disorders has created a favorable environment for the application of peptide therapeutics in the fields of oncology and metabolic disorders. According to data published by the International Diabetes Federation in 2021, there were 537 million adults (20-79 years) globally living with diabetes, which accounted for approximately 1 in 10 individuals. Additionally, 541 million adults were identified as having Impaired Glucose Tolerance (IGT), putting them at a high risk of developing type 2 diabetes. Peptide therapies like Glucagon-like peptide-1amide have gained popularity in pancreatic therapy as they stimulate insulin secretion postprandially. Consequently, the increasing number of diabetic patients is expected to drive the demand for peptide drugs and contribute to market growth in the foreseeable future.
The peptide synthesis market has also witnessed significant expansion due to increased research activities, novel product approvals, and enhanced funding for research and development. Furthermore, advancements in peptide synthesizers have provided additional advantages, further fueling market growth. An example of recent progress in this field is ISSAR Pharma’s announcement in April 2021 regarding the licensing of their peptide-based New Chemical Entities (NCEs), which have reached the pre-investigational new drug (IND) filing stage and obtained a United States patent. These notable developments in peptide drugs are expected to create a surge in market demand and drive the overall growth of the industry.
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Market Restraints and Challenges
The peptide synthesis market faces several restraints that can hinder its growth and development. Firstly, the high cost of peptide synthesis, including equipment, reagents, and skilled labor, presents a significant barrier for entry and limits the accessibility of peptide synthesis technologies. Additionally, the complexity and time-consuming nature of peptide synthesis processes pose challenges in terms of scalability and efficient production, limiting the ability to meet the growing demand for peptides in various fields such as pharmaceuticals and biotechnology. Furthermore, regulatory constraints and safety concerns related to the use of peptides, especially in therapeutic applications, impose strict guidelines and approval processes, leading to delays and additional costs. These restraints collectively impede the expansion and advancement of the peptide synthesis market.
Global Peptide Synthesis Market Segmentation
By Product
- Equipment
- Reagents & Consumables
- Others
By Technology
- Solid Phase Peptide Synthesis (SPPS)
- Liquid Phase Peptide Synthesis (LPPS)
- Hybrid & Recombinant Technology
By Application
- Therapeutics
- Diagnosis
- Research
By End-user
- Pharmaceutical & Biotechnology Companies
- Contract Development & Manufacturing Organization/Contract Research Organization
- Academic & Research Institutes
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Major Players in the Global Peptide Synthesis Market
Market players are focusing on strategic collaborations to enhance their product offerings. Some prominent participants in the global Peptide Synthesis market include Bachem Holding AG, Thermo Fisher Scientific, Merck KGaA, GenScript Biotech Corporation, Kaneka Corporation, Biotage AB, Syngene International Ltd. , Mesa Laboratories inc. , CEM Corporation and ProteoGenix among others.
COVID-19 Impact:
The peptide synthesis market has witnessed a significant impact due to the emergence of COVID-19, as peptides are increasingly being developed and repurposed in the search for therapeutics to treat the virus. According to an update from ClinicalTrials.gov in August 2022, over 100 peptide drugs are currently under development for treating COVID-19, including 15 synthetic peptides specifically targeting acute respiratory distress syndrome (ARDS) and other respiratory illnesses caused by SARS-CoV-2 infection. A 2022 article titled “Peptide-Based Vaccines and Therapeutics for COVID-19” highlighted the usefulness of peptides in addressing the urgent need for alternative COVID-19 therapies. Peptides offer advantages such as target selectivity, improved interactions, and reduced toxicity. Furthermore, minor structural modifications can enhance their metabolism, allowing for prolonged and long-acting effects. Consequently, the peptide synthesis market has experienced a significant impact due to the influence of COVID-19.
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Research Scope
- Scope – Highlights, Trends, Insights. Attractiveness, Forecast
- Market Sizing – Product Type, End User, Offering Type, Technology, Region, Country, Others
- Market Dynamics – Market Segmentation, Demand and Supply, Bargaining Power of Buyers and Sellers, Drivers, Restraints, Opportunities, Threat Analysis, Impact Analysis, Porters 5 Forces, Ansoff Analysis, Supply Chain
- Business Framework – Case Studies, Regulatory Landscape, Pricing, Policies and Regulations, New Product Launches. M&As, Recent Developments
- Competitive Landscape – Market Share Analysis, Market Leaders, Emerging Players, Vendor Benchmarking, Developmental Strategy Benchmarking, PESTLE Analysis, Value Chain Analysis
- Company Profiles – Overview, Business Segments, Business Performance, Product Offering, Key Developmental Strategies, SWOT Analysis.
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