Genome Editing Market: Key Developments and Market Forecast up to 2033

Market Definition

The genome editing market encompasses technologies and tools designed to alter the DNA of living organisms with precision. These technologies enable researchers and clinicians to make specific changes to genetic material, including the addition, deletion, or modification of genes. Genome editing is utilized across various fields, including medicine, agriculture, and biotechnology, to address genetic disorders, enhance crop traits, and advance scientific research.

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Market Outlook

The genome editing market is experiencing robust growth driven by technological advancements, increasing research activities, and the rising prevalence of genetic disorders. Genome editing technologies, such as CRISPR-Cas9, TALENs (Transcription Activator-Like Effector Nucleases), and ZFNs (Zinc Finger Nucleases), have revolutionized the ability to modify genetic sequences with high precision, offering new possibilities for therapeutic interventions and scientific discoveries.

One of the primary drivers of market growth is the increasing application of genome editing in medical research and therapeutic development. The ability to correct genetic mutations associated with various diseases, including cancer, genetic disorders (e.g., cystic fibrosis, muscular dystrophy), and infectious diseases, holds significant promise for personalized medicine and targeted therapies. Ongoing research and clinical trials are exploring the potential of genome editing to treat or even cure previously untreatable conditions, thereby driving investment and interest in this technology.

In agriculture, genome editing is being used to develop crops with improved traits such as resistance to pests, enhanced nutritional content, and better adaptation to environmental conditions. The growing demand for sustainable agriculture and food security is fueling the adoption of genome editing technologies to create high-yield, resilient crops. This application of genome editing is expected to contribute to increased agricultural productivity and address global food challenges.

Technological advancements are a key factor in the expansion of the genome editing market. Innovations such as base editing, prime editing, and advanced delivery systems are enhancing the precision, efficiency, and safety of genome editing techniques. These advancements are making genome editing more accessible and effective for a broader range of applications.

Regulatory developments and ethical considerations are also shaping the market. As genome editing technologies advance, regulatory bodies are working to establish guidelines and standards to ensure their safe and ethical use. The evolving regulatory landscape will influence the market dynamics and the pace of adoption of genome editing technologies.

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Research Objectives

  • Estimates and forecast the overall market size for the total market, across product, service type, type, end-user, and region
  • Detailed information and key takeaways on qualitative and quantitative trends, dynamics, business framework, competitive landscape, and company profiling
  • Identify factors influencing market growth and challenges, opportunities, drivers and restraints
  • Identify factors that could limit company participation in identified international markets to help properly calibrate market share expectations and growth rates
  • Trace and evaluate key development strategies like acquisitions, product launches, mergers, collaborations, business expansions, agreements, partnerships, and R&D activities
  • Thoroughly analyze smaller market segments strategically, focusing on their potential, individual patterns of growth, and impact on the overall market
  • To thoroughly outline the competitive landscape within the market, including an assessment of business and corporate strategies, aimed at monitoring and dissecting competitive advancements.
  • Identify the primary market participants, based on their business objectives, regional footprint, product offerings, and strategic initiatives

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Market Segmentation

The report analyses the global Genome Editing Market based on technology, delivery method, mode, application, end-use, and region.

Global Genome Editing Market by Technology

By Technology, the Genome Editing market is segmented into Mega nucleases, (CRISPR)/Cas9, TALENs/MegaTALs, ZFN, and Others. Among them, the CRISPR/Cas9 segment dominated the market and had the significant revenue share in 2023. This method can accurately cut DNA strands and insert new genetic information, making it a very useful and popular tool. CRISPR/Cas9 is simple, highly efficient, precise, and can be used for many different applications like gene therapy, drug development, scientific research, agriculture, and animal breeding. The use of CRISPR for clinical applications to treat diseases like AIDS, cancer, and genetic disorders has been widely accepted, as seen by the growing number of ongoing clinical trials using this gene-editing technique. Hence, aforementioned factors will enhance the segment growth.

Global Genome Editing Market by Delivery Method

By Delivery Method, the Genome Editing market is segmented into Ex-vivo, and In-vivo. Out of these the ex-vivo (outside the body) delivery method segment generated the significant revenue in 2023. This is because ex-vivo delivery offers advantages like more control over DNA modifications. The increasing number of clinical trials using genome editing tools has driven growth in the ex-vivo delivery segment, as this delivery method is being used more often. As a result of the successful Human Genome Project, almost 7,000 new human genetic diseases have been discovered. While ex-vivo gene editing-based gene therapies like CAR-T have had a significant impact, most patients with genetic diseases require in-vivo (inside the body) treatments. This requires precise editing tools and safe, targeted delivery systems that can be scaled up to help the entire patient population. This factor is contributing to the growth of the in-vivo segment.

Global Genome Editing Market by Mode

By Mode, the Genome Editing market is segmented into Contract, and In-house. Among them, the contract segment was accounted for the significant revenue share. This is due to there is a high level of outsourcing activities in the gene editing field, driven by the lower costs and greater operational flexibility offered by outsourcing compared to in-house development. The contract segment is expected to grow further due to the increasing capabilities offered by key companies in this domain. In December 2022, a contract research organization (CRO) company named Crown Bioscience collaborated with ERS Genomics Limited. This gave Crown Bioscience access to ERS’s CRISPR/Cas9 patent portfolio and strengthened its market presence in the gene editing space. Such initiatives are expected to boost the outsourcing opportunities in the genome editing field and can positively impact the overall market growth.

Global Genome Editing Market by Application

By Applications, the Genome Editing market is segmented into Genetic Engineering, and Clinical Applications. The genetic engineering segment was accounted for the significant revenue share. This large share is due to the rapidly growing fields of gene therapy and stem cell therapy. The use of CRISPR gene editing in human induced pluripotent stem cells (hiPSCs) has important implications for stem cell research to treat various diseases. Cell line engineering involves modifying the genetic material in cells to produce or change an organism’s traits. It has several applications in biotechnology, gene therapy, and drug development. Cell line engineering is used in many research initiatives and has the potential to transform medicine. The market for cell line engineering is expected to grow rapidly in the near future because of advancements in technology and the increasing need for personalized medicine tailored to an individual’s genetics.

Global Genome Editing Market by End-use

By End-Use, the Genome Editing market is segmented into biotechnology & pharmaceutical companies, academic & government research institutes, and contract research organizations. Among these, the biotechnology and pharmaceutical companies segment was accounted for the significant market share in 2023. This is attributed to the growing number of research activities by these companies to develop new therapies. Major global pharmaceutical companies are also partnering with emerging companies to create new technologies. Increased research and development efforts for novel treatments are the main factors driving revenue growth in this segment.

Additionally, an increase in strategic partnerships and agreements between key players in the market is expected to fuel further market expansion. For example, in January 2022, CRISPR Therapeutics and Capsida Biotherapeutics formed a strategic agreement to create innovative gene therapies using CRISPR/Cas9 technology for treating various diseases. As part of the agreement, Capsida will provide its virus-based delivery technology, while CRISPR Therapeutics will contribute its expertise in genome editing. Thus, abovd=edmentioned factors will create new growth opportunities for the biotechnology and pharmaceutical companies, thereby boost the industry growth.

Major Players

The key players in the market are CRISPR Therapeutics (Switzerland), Editas Medicine (United States), Intellia Therapeutics (United States), Sangamo Therapeutics (United States), Precision Biosciences (United States), Synthego (United States), Cellectis (France), Horizon Discovery Group (United Kingdom), GenScript Biotech Corporation (China), Bluebird Bio (United States), Integrated DNA Technologies, Inc., Beam Therapeutics, Thermo Fisher Scientific, and Caribou Biosciences, Inc., among others.

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Research Scope

  • Scope – Highlights, Trends, Insights. Attractiveness, Forecast
  • Market Sizing – Product Type, End User, Offering Type, Technology, Region, Country, Others
  • Market Dynamics – Market Segmentation, Demand and Supply, Bargaining Power of Buyers and Sellers, Drivers, Restraints, Opportunities, Threat Analysis, Impact Analysis, Porters 5 Forces, Ansoff Analysis, Supply Chain
  • Business Framework – Case Studies, Regulatory Landscape, Pricing, Policies and Regulations, New Product Launches. M&As, Recent Developments
  • Competitive Landscape – Market Share Analysis, Market Leaders, Emerging Players, Vendor Benchmarking, Developmental Strategy Benchmarking, PESTLE Analysis, Value Chain Analysis
  • Company Profiles – Overview, Business Segments, Business Performance, Product Offering, Key Developmental Strategies, SWOT Analysis

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