Opioid Market is expected to reach USD 28.45 billion by 2034, growing at a CAGR of 1.8%

The global opioid market size is expected to reach USD 28.45 billion by 2034, exhibiting a CAGR of 1.8% during 2025–2034.

The Opioid Market revolves around the production, distribution, and consumption of opioids, a class of drugs primarily used for pain management, anesthesia, and treatment of chronic conditions such as cancer-related pain. These drugs, which include natural, synthetic, and semi-synthetic opioids, have both therapeutic and illicit applications. Common opioids include morphine, oxycodone, hydrocodone, fentanyl, and tramadol.

Market Growth Drivers

Increasing Prevalence of Chronic Pain:
Rising incidences of conditions such as arthritis, cancer, and lower back pain are driving the demand for effective pain management solutions, including opioids.
Growing Geriatric Population:
With aging populations worldwide, there is an increasing prevalence of chronic pain disorders that require opioid prescriptions.
Post-Surgical Pain Management:
Surgeries often necessitate short-term use of opioids for pain control, particularly in orthopedics and trauma cases.

List of Key Companies in Opioid Market

Aurobindo Pharma Limited
Assertio Therapeutics, Inc.
AbbVie Inc.
Actavis Plc.
Amneal Pharmaceuticals LLC
Boehringer Ingelheim International GmbH
Cadila Healthcare Limited
Fresenius Kabi
Mallinckrodt Pharmaceuticals
Endo International plc

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Key Trends

Shift Toward Abuse-Deterrent Formulations:
ADF opioids incorporate technologies to prevent crushing, injecting, or snorting, addressing the risk of misuse.
Rising Preference for Non-Opioid Alternatives:
Non-opioid pain relievers, such as NSAIDs and nerve-blocking treatments, are gaining popularity, especially in the wake of the opioid epidemic.
Stringent Regulatory Measures:
Governments worldwide are implementing strict guidelines for opioid prescriptions, emphasizing monitoring systems to curb misuse.

Opioid Market Industry Developments

June 2024: Trevena, Inc. announced that its partner in China, Jiangsu Nhwa Pharmaceutical Co., received formal approval from the National Medical Products Administration (NMPA) for OLINVYK. The opioid has been authorized for use in adults to manage severe acute pain that requires intravenous opioid analgesics and is unresponsive to alternative treatments.

January 2023: Neuraxpharm revealed the launch of Neuraxpharm Belgium, expanding its presence to cover Belgium and Luxembourg. This move completes the company’s establishment in Benelux as part of its ongoing growth strategy across Europe.

𝐒𝐞𝐠𝐦𝐞𝐧𝐭𝐚𝐥 𝐎𝐯𝐞𝐫𝐯𝐢𝐞𝐰:

The research report categorizes the market into various segments and sub-segments. The primary segments covered in the study include type, application, end use and region. The splitting of the market into various groups enables businesses to understand market preferences and trends better. Also, stakeholders can develop products/services that align with the diverse needs of consumers in the industry. Besides, the research study includes a thorough examination of all the major sub-segments in the market.

By Class Outlook (Revenue – USD Billion, 2020–2034)

Natural
Semi-Synthetic
Fully Synthetic

By Product Outlook (Revenue – USD Billion, 2020–2034)

Codeine
Fentanyl
Oxycodone
Methadone
Morphine
Hydrocodone
Tramadol
Propoxyphene
Others

By Release Type Outlook (Revenue – USD Billion, 2020–2034)

Immediate-Release/Short-Acting Opioid
Extended-Release/Long-Acting Opioid

By Application Outlook (Revenue – USD Billion, 2020–2034)

Pain Management
Neuropathic
Migraine
Orthopedic and Musculoskeletal
Arthritis
Fibromyalgia
Others
Cancer Pain
Brain
Breast
Colorectal
Blood
Skin
Prostate
Others
Cough Treatment
Analgesia
Diarrhea Treatment
De-addiction
Others

The Opioid Market is navigating a transformative phase, balancing its critical role in pain management with growing societal and regulatory pressures to curb misuse. Innovations in abuse-deterrent formulations, expansion in emerging markets, and advancements in non-opioid alternatives are shaping the future of the industry. Collaborative efforts between stakeholders, including pharmaceutical companies, healthcare providers, and policymakers, will be essential to ensure safe and effective opioid use while addressing the ongoing challenges of addiction and misuse.

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