In chemical analysis, chromatography is a laboratory technique for separating a mixture into its components. The mixture is dissolved in a fluid solvent called the mobile phase, which carries it through a system on which a material called the stationary phase is fixed. Because the different constituents of the mixture tend to have different affinities the stationary phase is fixed. Because the different constituents of the mixture tend to have different affinities for the stationary phase and are retained for different lengths of time depending on their interactions with its surface sites, the constituents travel at different apparent velocities in the mobile fluid, causing them to separate. The separation is based on the differential partitioning between the mobile and the stationary phases. Subtle differences in a compound’s partition coefficient result in differential retention on the stationary phase and thus effect separation.
Chromatography may be preparative or analytical. The purpose of preparative chromatography is to separate the components of a mixture for later use and is thus a form of purification. This process is associated with higher costs due to its mode of production. Analytical chromatography is done normally with smaller amounts of material and is for establishing the presence or measuring the relative proportions of analytes in a mixture. The types of chromatography are ion exchange chromatography, gas chromatography, liquid chromatography, size exclusion chromatography, and affinity chromatography. With the increasing R&D activities and growing interest of stakeholders toward separation and purification techniques in the pharmaceutical industry, the demand for chromatography techniques.
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Global Chromatography Market – Competitive Landscape
On October 7, 2022, Water Marks 25 years in Ireland with USD 6.52 million clinical diagnostics R&D Center Expansion in Wexford. On June 19, 2022, Trajan acquired a leading chromatography consumables and tools business building critical mass in the gas chromatography portfolio.
Some of the Key Players in the Global Chromatography Market Include –
- Agilent Technologies
- Bio-Rad Laboratories
- Danaher Corporation
- Hitachi Ltd.
- Merch KGAA
- PerkinElmer, Inc.
- Restek Corporation
- Shimadzu Corporation
- Phenomenex Inc.
- Thermo Fisher
Global Chromatography Market – Growth Drivers
Ongoing advancements in pharmaceutical and biotechnological research drive the demand for chromatography in drug discovery development, and quality control, fostering market growth. The increasing global demand for generic drugs necessitates stringent quality control measures, with chromatography playing a vital role in ensuring the purity and efficacy of pharmaceutical products. According to the National Center for Biotechnology Information (NCBI), American purchasers spend about USD 103 billion per year on generic drugs. The growth of biopharmaceuticals, including monoclonal antibodies and therapeutic proteins, boosts the demand for chromatography techniques in downstream processing, purification, and analysis. Growing environmental awareness and stringent regulation regarding pollutant monitoring contribute to adopting chromatography in environmental testing, water analysis, and air quality assessment. Chromatography addresses the need for accurate analysis in the food and beverage industry, ensuring product safety, quality, and compliance with regulatory standards, thereby driving the market growth of global chromatography. The expanding scope of research and development activities in diverse industries, such as life sciences, chemistry, and material science, fuels the demand for chromatography tools and solutions.
Global Chromatography Market – Restraints
The substantial upfront investment required for chromatography equipment and consumables can be a deterrent for smaller research laboratories and organizations, limiting widespread adoption—installation cost of chromatography up to USD 1,000 to USD 3,000. Beyond the initial investment, the ongoing operational costs, including maintenance, consumables, and skilled personnel, contribute to the total cost of ownership, posing a challenge for budget-constrained laboratories. The sophisticated nature of chromatography techniques requires specialized training and expertise, leading to a shortage of skilled professionals. This complexity can hinder the seamless integration of chromatography solutions into various industries. The chromatography market faces competition from alternative analytical technologies that may offer cost-effective or faster solutions for certain applications, impacting the market share of chromatography systems. Stringent regulatory requirements, especially in industries like pharmaceutical and food safety, can pose challenges for chromatography users in terms of compliance, documentation, and validation, adding complexity to the analytical processes. Disposal of chromatography consumables, such as columns and solvents, raises environmental concerns. Compliance with environmental regulations adds an extra layer of complexity and cost to chromatography processes.
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Global Chromatography Market – Opportunities
Ongoing development in chromatography techniques and equipment creates opportunities for manufacturers to introduce innovative solutions, enhancing efficiency and accuracy in various applications. With the rising demand for pharmaceuticals, chromatography plays a crucial role in drug development, quality control, and research. The expanding pharmaceutical sector presents a significant opportunity for chromatography market growth. Growing awareness of environmental concerns and the need for monitoring pollutants drive the demand for chromatography in environmental testing. Government regulations on environmental protection contribute to increased adoption.
Global Chromatography Market – Geographical Insight
The market for global chromatography is segmented into regions such as North America, Latin America, Europe, Asia-Pacific, the Middle East & Africa. North America is the largest market for global chromatography due to advanced healthcare infrastructure, robust pharmaceutical, and biotechnology industries, and a focus on research and development. Major chromatography equipment manufacturers and suppliers are concentrated in the United States, contributing to the region’s market dominance. Europe is a prominent region for chromatography market growth, with strong support for research and development activities. The pharmaceutical and biotechnology sectors in countries like Germany and the UK fuel demand. Asia-Pacific region experienced robust growth in the chromatography market, fueled by expanding pharmaceutical and biotechnology industries, increasing investment in healthcare infrastructure, and a growing emphasis on research and development.
Global Chromatography Market – Key Development
- On September 6, 2023, Restel Leverages Oracle Expertise from Mastek to enhance chromatography online solutions.
- On June 12, 2023, Agilent Introduced a new comprehensive GPC/SEC Solution at the HPLC 2023 Conference.
- On March 28, 2023, AmbioPharm utilized YMC Twin-Column Chromatography in large-scale peptide production.