Collagen is the main structural protein in the extracellular matrix found in the body’s various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole-body protein content. Collagen consists of amino acids bound together to form a triple helix of elongated fibril known as a collagen helix. It is mostly found in connective tissue such as cartilage, bones, tendons, ligaments, and skin. Collagen makes up 30% of the protein found in the human body. Vitamin E improves the production of collagen. Depending on the degree of mineralization, collagen tissue may be rigid or compliant or have a gradient from rigid to compliant. Collagen is also abundant in discs and dentin in teeth. In muscle tissue, it serves as a major component of the endomysium. Collagen constituents one to two percent of muscle tissue and accounts for 6% of the weight of the skeletal muscle tissue. The fibroblast is the most common cell that creates collagen. Gelatin, which is used in food and industry, is collagen that has been irreversibly hydrolyzed using heat, basic solution, or weak acids.
First, a three-dimensional stranded structure is assembled, with the amino acids glycine and proline as its principal components. This is not yet collagen but its precursor, procollagen. Procollagen is then modified by the addition of hydroxyl groups to the amino acids proline and lysine. This step is important for later glycosylation and the formation of the triple helix structure of collagen. Because the hydroxylase enzymes that perform these reactions require vitamin C as a cofactor, a long-term deficiency in this vitamin results in impaired collagen synthesis and scurvy. The synthesis of collagen occurs inside and outside of the cell. Collagen cremes are widely sold even though collagen cannot penetrate the skin because its fibers are too large. Most research on collagen supplements has been funded by industries.
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Global Collagen Market – Competitive Landscape
On November 3, 2023, BASF joined forces with 3Helix, a US-based start-up specializing in collagen-hybridizing peptide technology. On October 23, 2023, LBB Specialities, a leader in specialty chemicals and ingredient distribution in North America, announced a partnership with Viscofan DE, a global leader in collagen manufacturing. On October 2, 2023, Chinese synthetic collagen maker Trautec secured USD 27 million for series B. On August 22, 2023, Jellatech landed USD 3.5 million to produce animal-free collagen. On July 20, 2023, 3D BioFibR raised USD 3.52 million to bring its premium collagen fiber products to market. On April 20, 2021, Carabao Group launched a woody C+ lock collagen mixed berry with USD 100 million -baht investment.
Some of the Key Players in the Global Collagen Market Include –
- Tessenderlo Group
- Darling ingredients
- Gelita AG
- Lapi Gelatine S.P.A.
- Holista Colltech
- Gelnex
- Nitta Gelatin N.A. Inc.
- Collagen Solutions Plc.
- Royal DSM N.V.
- Weishardt Holding S.A.
Global Collagen Market – Growth Drivers
Growing global aging demographics contribute to a heightened demand for collagen in anti-aging products and supplements. Increasing consumer awareness and focus on health and wellness drive the demand for collagen as a key ingredient in nutritional supplements and functional foods. Collagen’s widespread use in cosmetics and personal care products is fueled by a desire for skin care solutions and anti-aging formulations. Continuous research and development in medical applications, such as wound healing, tissue engineering, and regenerative medicine, boosts collagen demand in the healthcare sectors. Collagen’s versatility led to its adoption in various industries, including pharmaceuticals, food and beverages, and medical devices, contributing to overall collagen market growth. Rapid urbanization and lifestyle changes influence consumer preferences, with collagen becoming popular as a health and beauty supplement. Growing interest in nutraceuticals and functional foods propels the demand for collagen as a key ingredient offering health benefits. Ongoing innovation by collagen market players, introducing new collagen formulations and products, attracts consumers and drives market expansion. The increasing prevalence of e-commerce channels provides a broader reach for collagen-based products, contributing to collagen market growth in a digital era. According to Statista e-commerce sales were estimated to exceed USD 5.7 trillion worldwide.
Global Collagen Market – Restraints
Limited sources diversity, with bovine and marine collagen dominating the market of collagen, leading to concerns about sustainability and ethical sourcing. Stringent regulations and standards governing collagen production and usage, pose compliance challenges for collagen market players. Potential allergenicity associated with collagen from certain sources impacts consumer acceptance and poses a restraint on the collagen market growth. The cost-intensive nature of collagen production, including extraction, purification, and processing, can limit market accessibility and affordability. Intense competition among key market players may result in pricing pressures and reduced profit margins affecting overall market sustainability. Limited awareness among consumers, especially in certain regions, about the benefits and application of collagen, hindering collagen market growth potential. Competition from alternative ingredients and substitutes in the cosmetics, pharmaceutical, and food industries, impacts collagen market share. Cultural and dietary preferences influence collagen consumption, with certain regions showing resistance to adopting collagen-based products. Growing concerns about the environmental impact of collagen production, particularly from animal sources, influence consumer choices and market dynamics. Vulnerability to supply chain disruptions, such as diseases affecting livestock or disruptions in marine ecosystems, impacting the availability of collagen sources.
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Global Collagen Market – Opportunities
Expanding opportunities in cosmetics, pharmaceuticals, food, and beverages offering a broad range of applications for collagen-based products. Increasing consumer focus on health and wellness, driving demand for collagen supplements and functional foods. Untapped potential in developing regions, especially in Asia-Pacific and Latin America, where awareness of collagen benefits is growing. Growing interest and opportunities in plant-based collagen alternatives to cater to the rising demand for vegetarian and vegan products. Opportunities for market players, to innovate and develop new collagen formulations, contributing to product differentiation. Rising opportunities in the medical field, including wound healing, tissue engineering, and regenerative medicine, driving collagen demand. Increasing online presence and e-commerce channels provide new avenues for reaching a wider consumer base, especially in the digital age. Opportunities for personalized collagen products catering to specific health and beauty needs, align with the trend of individualized consumer preferences.
Global Collagen Market – Geographical Insight
The market for global collagen is segmented into regions such as North America, Latin America, Europe, Asia-Pacific, the Middle East & Africa. North America is the largest market for collagen due to high consumer awareness and demand for collagen-based products. Growing use of collagen in the pharmaceutical and cosmetic industries. In Europe significant market presence with a focus on collagen in medical applications. Increasing adoption in the food and beverage sector for functional and health-oriented products. Asia-Pacific is a rapidly expanding market for collagen products in the beauty and personal care sectors. Potential for market expansion as consumer awareness increases.
Global Collagen Market – Key Development
- On November 14, 2023, GELITA presents the first collagen solution for endurance athletes and its versatile ingredient portfolio.
- On August 2, 2023, Uniza Healthcare strengthened the Derma range and launched Aurelius, Gold, and Collagen serum masks.
- On June 29, 2023, 3D BioFibR released two new 3D bioprinting collagen fiber products.
- On April 21, 2023, Global Supplement Leader, Biosil® launched new collagen-generating capsules.
- On August 15, 2022, Revive Collagen launched the world’s first clinically proven liquid vegan collagen using ground-breaking science.