Mice are used for experiments because they have a genetic makeup that is capable of imitating nearly any human disease or condition, therefore mice are the most frequently used animal model for researching human disease. The specific mutations occurring in humans causing disease can be implanted into mice using contemporary sequencing, genomic engineering techniques, etc., producing a more precise and valuable disease study model for data collection. To create genetically identical strains, mice can be inbred. This consistency makes the experiments more reproducible and accurate. Because mice live for shorter duration than humans, it is possible to study a mouse’s full life cycle in just two or three years. Mice are an essential tool for researching the developmental mechanisms by which the conserved mammalian genome gives rise to a wide range of diverse species, as well as for examining biological processes that have been conserved over the evolution of the rodent and primate lineages.
The global market for mouse models provides a wide range of rodent models and services for applications in oncology, immunology, neurology, and other fields of study that play a crucial role in drug development, disease studies, etc. Mice models are widely employed in the early stages of development by most of the laboratories for research and the biopharmaceutical industry to investigate the in vivo efficacy, mechanism of action, and side effects of sample underestimation.
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Global Mice Model Market – Competitive Insight
In July 2020, The Institute d’Investigació Biomèdica de Bellvitge (IDIBELL) and the ICO team used an orthotropic mouse model to conduct a real-time personalized oncology study to determine the best treatment option for a type of recurrent sarcoma.
In September 2021GemPharmatech Co., Ltd. (GPT) attended the Biologics UK Oxford Global Conference to present humanized mouse models to aid the pre-clinical development of COVID-19.
In January 2022, Inotiv acquired Orient BioResource Center, Inc., a preclinical CRO and animal model supplier based in Seongnam, South Korea.
Some of the Key Players in the Global Mice Model Market Include –
- Charles River Laboratories (US)
- Inotiv (US)
- THE JACKSON LABORATORY (US)
- GemPharmatech (China)
- Cyagen (US)
- Shanghai Model Organisms Center, Inc. (China)
- JSR Corporation (Japan)
- Biocytogen (China)
- TRANS GENIC INC. (Japan)
- Ozgene Pty Ltd. (Australia)
- Taconic Biosciences, Inc. (US)
- TransCure bioServices (France)
- Harbour BioMed (China)
- Marshall BioResources (US)
- genOway (France)
- Vivo Bio Tech Ltd. (India)
- ingenious targeting laboratory (US)
- Janvier Labs (France)
- Applied StemCell (US)
- Creative Animodel (US)
- JOINN Laboratories Co., Ltd. (China)
- Creative Biolabs (US)
- Crescendo Biologics (UK)
- Aragen Life Sciences (India)
- PolyGene (Switzerland)
- and Among Others
Global Mice Model Market – Growth Drivers
The growth of this market is mainly due to the increasing prevalence of chronic diseases such as cancer and an increasing number of pre-clinical research projects. Increasing the expenditure on research and development in the pharmaceutical and biotechnology industry is one of many reasons for driving Global Mice market growth. In the analytical health market, due to the increase in research funding for new drug development in the region, the growth of the mouse model market will be supported as it provides a means to identify the activity of suspected compounds in humans.
The growth of the mice model market is directly proportional to each life sciences company providing cutting-edge research tools to the pharmaceutical industry, biotechnology, and academic institutions, always updating the models with the latest findings and following animal safety guidelines. That being the reason for the growth in the market is the government acceptance of the data generated by the Mice model being the minimum requirement for filing for Clinical studies on humans that is an IND application.
The COVID-19 pandemic has created many opportunities for market participants. The introduction of mouse models to study the advancements made in the development and utilization of relevant mouse types after the discovery of SARS-CoV-2 will amplify market growth during the pandemic. The rise of personalized medicine is increasing the demand for humanized rat and mouse models worldwide.
Global Mice Model Market – Restraints
Even while humans and mice are connected phylogenetically, they have developed to be extremely distinct creatures because they have adapted to and evolved in various settings. Mice frequently react to experimental manipulations in ways that are remarkably different from those of humans. However, because the networks connecting genes to disease are expected to be different between the two species, mice are not as dependable in mimicking humans as models of disease. When using mice in biomedical research, it’s important to consider both the evolutionary differences and similarities between mice and Humans. Mouse research faces challenges due to evolved differences, poor housing conditions, same-sex groups, and lack of physical exercise. Research is often carried out on young animals, causing cold stress, sleep deprivation, and hypertension. Mouse cells are more sensitive to oxygen damage, but cell culture studies are often conducted in 20% oxygen, damaging them more. There are no agreed standards for the design, analysis, or publication of mouse research, leading to substandard statistical analysis and potential publication biases.
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Global Mice Model Market – Opportunities
The growth drivers like Drug Discovery & Development, Research Applications, and Personalized Medicine are responsible for creating new opportunities for the market for the person knowing about the mice model. There is a steady growth in opportunities after the hike of the post-pandemic period. As new human disease-specific mice models are made available easily, which makes the researchers work quickly and easily. Personalized modifications to the mice model as per the experiment can be mentioned in the requirement to the provider which in turn increases more specificity of the experiment. These mice models also allow for more thorough studies into the mechanisms behind the disease in humans as well as the assessment of possible treatments. For example, the increased interest in cancer research has resulted in a demand for mouse models that are designed to replicate different types of cancer. Neurodegenerative disorders like Parkinsonism, Alzheimer’s disease, etc. also need mice models for research and potential interventions.
Global Mice Model Market – Geographical Insight
The region’s increasing research investment in the area of innovative medication development is the main factor driving the growth of the mice model market in Asia Pacific. The mouse model market is divided into five geographic segments: North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. Europe was second in line for dominance, behind North America. When it comes to funding research for the creation of novel, cutting-edge therapies, North America has taken the lead. Thus, the creation of new treatments, R&D initiatives made by nations like the US and Canada, and an increase in preclinical research projects in the area are all factors supporting the expansion of the North American market.
Global Mice Model Market – Key Development
- In December 2023, Biocytogen and Nuerocrine Biosciences signed a licensing agreement. Under the terms of this agreement, Neurocrine Biosciences is permitted to license specific AR bodies for the development, production, and global marketing of therapeutic products.
- In July 2023, With Charles River Laboratories, GemPharmatech reached a strategic licensing deal for the distribution of their next-generation NOD CRISPR Prkdc II2r gamma (NCG) mice lines throughout North America.
- In April 2022, Histion, LLC was acquired by Inotiv. The acquisition is a calculated move that showcases the company’s growing capacity to provide pathology and surgical model services.