Stem cells are the type of cells that can renew themselves. Stem cells can develop into many different types of cells in the body during its early life and growth. Types of stem cells include pluripotent stem cells and somatic or adult stem cells. The number of adult stem cells serves as an integral part of internal repair systems that generate replacements for the cells that are lost due to normal injury, wear and tear, or certain diseases. These stem cells remain non-dividing for a large period unless they are needed for more cells to maintain and repair the tissues. Pluripotent stem cells can differentiate into all the cells of the adult human body. Stem cell’s abilities are unique which include the ability to renew themselves and the ability to recreate functional tissues. Unlike other cells, stem cells divide many times. When a stem cell divides, it may be two daughter cells which are both stem cells, a stem cell and differentiated cell, or both differentiated cells. Pluripotent stem cells are undifferentiated and do not contain any tissue-specific characteristics. Yet pluripotent cells can give rise to all differentiated cells in the human body like heart muscle cells, nerve cells, and blood cells.
The degree of potency of the stem cells varies i.e. the number of different cell types they can form varies. While differentiating, the cell usually goes through several stages, becoming more specialized at each step. Due to their unique regenerative abilities, stem cells are used in biomedical research and also in cell-based therapies. Tissue engineering which is an application of stem cells for the generation of cell-based therapies is widely used. To realize the potential of the stem cell for a particular therapy, scientists must be able to manipulate the stem cells so that cells possess the necessary characteristics. Therapies based on stem cells are used to treat diseases like anemias, blood disorders or inherited red cell abnormality, bone marrow cancers, leukemia, lymphoma, inherited immune disorders, inherited metabolic disorders, inherited platelet abnormalities, phagocyte disorders, and solid tumors. Thus in stem cell therapies, the body’s cells i.e. stem cells are used in the treatment of the diseases.
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Global Stem Cell Market– Competitive Insight
On Jan 19, 2024, STEMCELL Technologies acquired Propagenix Inc., a Maryland-based biotech company, which will contribute to big advancements in scientific research in both labs and clinical settings for the treatment of cancer, airway disease, and other disorders.
On Nov 21, 2022, Merck acquired Imago BioSciences, Inc. which is a clinical-stage biopharmaceutical company, with a vision to strengthen its presence in the growing field of hematology.
Some of the Key Players in the Global Stem Cell Market Include –
- Thermo Fisher Scientific
- STEMCELL Technologies Inc.
- Merck KGaA (Sigma Aldrich)
- CellGenix GmbH
- PromoCell GmbH
- Takara Bio
- Lonza
- Cellartis AB
- Becton, Dickinson and Company
- PLURISTEM THERAPEUTICS INC.
- Smith & Nephew PLC
- Pluristem Therapeutics Inc.
- Qiagen NV
- AllCells LLC
- Miltenyi Biotec
- International Stem Cell Corporation
- ReNeuron Group plc
- Regen BioPharma
- Magellan
- Medipost Co., Ltd
Global Stem Cell Market– Growth Drivers
Stem cells are used widely in the therapies for the treatment of various diseases like anemias, blood disorders or inherited red cell abnormality, bone marrow cancers, leukemia, lymphoma, inherited immune disorders, inherited metabolic disorders, inherited platelet abnormalities, phagocyte disorders, and solid tumors. The wide use of stem cells thus contributes to the growth of the global stem cell market. There has been a significant rise in the cases of cancer every year throughout the world. According to a report by WHO, cancer was the leading cause of death and caused nearly 20 million deaths in the year 2020. The most common cancers in 2020 (in terms of new cases) were: breast, lung, colon and rectum, prostate, skin (non-melanoma), and stomach. The most common causes of cancer death in 2020 were lung, colon and rectum, liver, stomach, and breast. Thus the increase in the prevalence of cancer all over the globe provides growth opportunities as stem cells are primarily used in the treatment of cancer like cancer related to the blood, thus making it another prominent market driver for the stem cell market. Technological advancements in cell therapy and an increase in the importance of personalized therapies also act as the growth driver for the particular market. An increase in awareness in people about the potential of stem cell therapies also leads to an increase in its usage and driving the market forward.
Global Stem Cell Market– Restraints
Despite its uses, stem cells have some cons. Adult stem cells cannot grow for long periods in culture, they are a very small number in each tissue making them difficult to find and purify and there are no technologies to develop large quantities of adult stem cells in the culture. Embryonic stem cells if directly used from undifferentiated culture preparation for tissue transplant, then they can cause tumors or cancer development. So, these are some of the drawbacks of stem cell therapies which may act as the restraints for the particular market. Again, there is a risk of rejection or complications in stem cell therapy, thus forming another market restraint. Sometimes lack of standardization will lead to inconsistent results and can hinder market growth.
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Global Stem Cell Market– Opportunities
Growth in the number of chronic diseases throughout the world provides immense opportunities for growth in the particular market. Personalized therapies have immense potential as it is based on the individual genetic makeup, thus providing an effective solution for the treatment. Technological advancements play an important role in providing opportunities for growth in the market. Some of the stem cells are unable to develop in huge quantities in the cell culture, thus advancements in this field may also provide immense opportunities for growth in the global stem cell market. An increase in the number of cancerous patients also provides opportunities in the market as stem cells are primarily used in cancer therapies and for treatment of the cancer.
Global Stem Cell Market– Geographical Insight
The market for stem cells is segmented into regions such as North America, Latin America, Europe, Asia-Pacific, the Middle East & Africa. North America is the largest market for stem cells due to the presence of advanced technologies in the region. The presence of key market players contributes to research and development in the region. Europe is another prominent market for stem cells. The Asia Pacific region is showing considerable growth prospects. The market is further propelled by advancements in technology and infrastructure development. Africa is an emerging market for stem cells, with an increasing inclination towards technological advancements in the treatment of chronic diseases.
Global Stem Cell Market– Key Development
- On Jul 31, 2020, Thermo Fisher Scientific and Lyell Immunopharma partnered to develop manufacturing processes, to create more effective cell therapies which include stem cells, which will benefit cancer patients.