As per Global Insight services’ assessment, about 20+ prominent pharma and biotech giants are working on 20+ drugs in the Angina Pectoris – Drug Pipeline Landscape, 2023 globally. Angina Pectoris – Drug Pipeline Landscape, 2023 report by Global Insight Services provides a comprehensive analysis of the ongoing clinical development activities and growth prospect.
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Angina also known as angina pectoris, is a type of chest pain or discomfort that occurs when a part of the heart doesn’t get enough blood and oxygen, which is due to the spasm or obstruction of the arteries that supply the blood to the heart muscles. Angina is mainly of four types: stable angina, unstable angina, microvascular angina, and vasospastic or variant angina.
Angina is caused due to the built up of plaque in the arteries. The major risk factors that are concerned with angina are smoking, age, stress, lack of physical activity, family history of premature cardiovascular diseases. Medical conditions that exacerbate angina are diabetes, dyslipidaemia, hypertension, kidney disease, polycythaemia, and it is also concerned with the use of medications such as vasodilators.
Symptoms that are associated with angina are chest pain or discomfort. Pain around epigastrium, neck, shoulders and back. Autonomic symptoms include nausea, vomiting, pallor, shortness of breath, squeezing and fatigue.
Angina can be diagnosed with the primary complains including chest pain or discomfort, chest tightness and precipitated by cold weather or a meal. Electrocardiogram is recommended to determine the ST elevations. Non-invasive testing includes coronary angiogram. Imaging testing includes echocardiogram, CT and MRI.
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Angina treatment is aimed at providing sufficient oxygen supply to the heart. Common treatment options include anticoagulants, nitrates or calcium channel blocker, beta-blockers and statins. Angioplasty and sometimes coronary artery bypass grafting are recommended in severe disease condition. Lifestyle changes promotes towards healthier condition.
Major pharmaceutical companies are involved in the development of potential drug candidates to improve the Angina Pectoris treatment such as Ad5FGF-4, AR36, ACP-01 and others. Key players involved in the development of therapies to treat Angina Pectoris are Azurity Pharmaceuticals, Gene Biotherapeutics, Hemostemix Inc, Milestone Pharmaceuticals Inc, XyloCor Therapeutics Inc, and others. Two drugs are under late-stage Phase III clinical trials and four drugs are in Phase II clinical trials and some other drugs are under Phase I, Preclinical and Discovery stages of development.
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Report Covers the Emerging Pipeline Products Under Different Phases of Clinical Development Like –
– Late-stage products (Phase III)
– Mid-stage products (Phase II)
– Early-stage product (Phase I)
– Pre-clinical and Discovery stage candidates
– Discontinued & Inactive candidates
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